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PEG-bis-amine (Poly(ethylene glycol)-bis-amine) (MW 2000) is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs.
PROTACs are compounds containing two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets the protein of interest.
PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
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